Complex Lower Extremity Reconstruction Surgery at Stanford

Overview

Complex extremity reconstruction focuses on restoring function, appearance, and mobility to the lower limbs after severe trauma, infection, or cancer surgery. At Stanford Plastic & Reconstructive Surgery, our multidisciplinary team combines microsurgery, orthopedics, and vascular expertise to preserve limbs whenever possible and achieve the best possible functional and aesthetic results. Each plan is personalized to meet the patient’s recovery goals and improve quality of life.

Types of Complex Lower Extremity Reconstruction Surgery

Stanford offers both soft-tissue and bone reconstruction using advanced microsurgical techniques. These may include free tissue transfer, local flaps, skin grafting, and nerve or tendon repair. When limb salvage is possible, our surgeons work to reconstruct the leg’s appearance and strength; when amputation is unavoidable, we optimize outcomes for prosthetic use and comfort.

Microsurgical Free-Flap Reconstruction

Microsurgical free-flap transfer allows surgeons to move healthy tissue—skin, fat, muscle, or bone—from another part of the body to cover complex wounds in the leg or foot. These flaps restore blood supply and protection to underlying structures such as bones, tendons, and joints, often preventing amputation. Stanford surgeons are internationally recognized for their expertise in perforator flap and supermicrosurgical techniques.

Nerve and Tendon Repair

When trauma affects nerve or tendon function, reconstruction aims to restore motion and sensation. Techniques may include primary nerve repair, nerve grafting, tendon transfers, or nerve decompression. Stanford’s microsurgeons work closely with rehabilitation specialists to help patients regain as much strength and dexterity as possible.

Limb Salvage and Reconstruction After Trauma or Cancer

For patients with severe soft-tissue loss, chronic infection, or exposed bone following tumor removal, reconstruction can restore coverage, prevent infection, and maintain limb integrity. Procedures are designed to maximize durability and mobility, often combining orthopedic stabilization with soft-tissue coverage in a single stage.

Conditions & Treatments

Stanford provides comprehensive care for patients with traumatic, oncologic, or chronic lower extremity defects requiring advanced reconstruction.

Common conditions and treatments include:

  • Lower extremity trauma with tissue loss

  • Exposed bone, joint, or hardware

  • Chronic wound or infection (osteomyelitis)

  • Limb salvage after cancer resection

  • Free-flap reconstruction (ALT, DIEP, gracilis, or muscle flaps)

  • Nerve and tendon repair

  • Skin grafting or local flap coverage

  • Post-amputation revision and prosthetic optimization

Our Faculty

Subhro K. Sen, MD
Medical Co-Director, Advanced Wound Care Center (2014 - Present)
Anita Tanniru Mohan, MBBS, PhD, MBA
Instructor in Surgery, Mayo Clinic, Rochester, MN (2022 - 2022) Clinical Instructor, Stanford University (2022 - 2023) Clinical Assistant Professor, Stanford School of Medicine (2023 - Present)

Why Choose Us?

Stanford’s plastic surgeons are international leaders in microsurgical lymphedema treatment, offering state-of-the-art imaging and surgical precision. Our program emphasizes collaboration with oncology, vascular medicine, and rehabilitation specialists to deliver the most advanced, coordinated care available on the West Coast.

What to Expect

At your initial consultation, your surgeon will evaluate the cause, severity, and distribution of your swelling using advanced imaging and clinical assessment. You’ll receive a personalized treatment plan that may include conservative therapy, surgery, or a combination of both. After surgery, our team provides close follow-up and rehabilitation support to help you achieve lasting improvement in comfort, mobility, and confidence.

Make an Appointment

For Adult Clinic:

650-723-7001

Physician Referrals

Referring physicans may fax referral form with supporting documentation to 650-320-9443.